Acne Treatment and NONI

Acne (acne vulgaris) is a dermatologic condition characterized by lesions that most often appear on the face and neck, but also develop on the chest, back, shoulders and upper arms. Approximately 80 percent to 95 percent of adolescents develop some degree of acne. Acne is characterized by pimples, cysts and abscesses. It occurs when the pores in the skin are blocked, trapping oil, dead skin and bacteria in the hair follicles. Under normal circumstances, glands (called sebaceous glands) attached to hair follicles secrete an oily substance known as sebum. This sebum typically travels up the hair follicle and onto the skin. However, if the hair follicle is blocked, the sebum can’t get out, sometimes causing the formation of a blackhead. This is the result of the blocked oil oxidizing, causing inflammation and an influx of white blood cells. Meanwhile, normally present bacteria (Propionibacterium acnes) begin to break down the trapped sebum within the hair follicle. This results in further inflammation, as white blood cells attack the bacteria. Pus forms as the lesion enters the whitehead stage. In more severe stages, an abscess—a pus-filled pocket within the skin—may form. Although most pimples won’t leave lasting scars, anything that damages the dermis (the layer of skin just underneath the epidermis) can leave a permanent scar.
Types of Acne Lesions
• Open comedones (blackheads): These are dilated hair follicles that are filled with sebum, dead cells and bacteria, and which have central, dark, solid plugs. The follicles are not completely blocked; the black appearance is caused by oxidation, not dirt.
• Closed comedones (whiteheads): These form when skin cells and oil completely block the opening of a hair follicle, usually after a blackhead has formed.
• Nodules: These are solid, dome- or irregularly shaped, inflamed lesions that extend deep into the skin, sometimes causing tissue damage and scarring if not treated. Nodular acne, which can be painful, is the most severe form of the disease.
• Papules: This type of whitehead (5 mm or less) is one that has become swollen, red and inflamed
• Cysts: These sac-like lesions contain white blood cells, bacteria and dead cells in a liquid or semi-liquid state. They can result in scarring, and may be very painful and severely inflamed. Cysts and nodules often appear together to form nodulocystic acne, also very severe.
• Pustules: This whitehead is pus-filled and inflamed. Once they rupture into the skin, they form pustular heads.
Acne can be caused by environmental and genetic factors. The role of hormones in the development of acne is apparent at puberty, when there is a surge in the production of male hormones (which are present in both males and females), enlarging the sebaceous glands in the skin. This results in increased sebum production, which leads to the aforementioned plug formation, creating as well a fertile environment in which bacteria can multiple. Unlike male-hormone androgens, female-hormone estrogens have a beneficial effect on acne, which is why some doctors recommend birth control pills for women who have acne. But when a woman’s estrogen levels decline, as they do just before the beginning of a menstrual cycle, acne may worsen.
Acne or acne-like lesions can develop in response to various substances, including corticosteroids, lithium, and some psychotropic drugs. Use of many types of cosmetics, oil-based hair products, and suntan lotions can block oil glands and worsen acne.
Role of Noni

Noni for acne can help reduce inflammation, and infection. Acubin, L-asperuloside, and alizarin present in the Noni have the antibacterial activity. Other ingredients anthraquinone compounds are also proven antibacterial agents. These compounds have been shown to fight against infectious bacteria strains such as Pseudomonas aeruginosa, Proteus morgaii, Staphylococcus aureus, Baciillis subtilis, Escherichia coli, Salmonella, and Shigela.
Vitamins A and E. The benefits of vitamins A and E in acne was highlighted in a recent study in which investigators identified plasma vitamin A and E concentrations in 100 untreated patients with acne, compared with 100 healthy controls. Plasma concentrations of both vitamins in patients with acne were significantly lower than those of the controls, and a strong relationship between a decline in vitamin A and E levels and an increase in the severity of acne was noted (El-Akawi Z et al 2006). Noni contain abundant quantity of Vitamin A and E thus may help a lot in Acne cases
Lipoic acid. Research into the efficacy of lipoic acid in the treatment of acne goes back several decades. Reportedly, lipoic acid activates a factor in the body known as AP-1, which produces enzymes that digest damaged collagen and helps erase scars, including acne scars (Kovalev VM 1981a,b). Lipoic acid is an ingredient in several topical acne remedies. Noni contains the Lipoic acid in natural form
Zinc. This mineral appears to perform a threefold role in the treatment of acne. It helps reduce inflammation; kills Propionibacterium acnes, the main bacteria associated with the disease, and produces changes in the skin environment that make it more hostile to this bacterium for a longer time. In a double-blind study, a combination of 1.2 percent zinc and 4 percent erythromycin in a topical lotion was used by 14 individuals with acne. The combination significantly reduced secretion of sebum after six weeks of treatment. Noni contain this essential rare mineral and thus helps in Acne cases.
Essential Fatty Acids. The omega-3 fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) are well-known anti-inflammatories that have been shown in some studies to reduce inflammation. Several studies have found that omega-3 fatty acids are absorbed through the skin and can reduce inflammation in a particular area .
Noni contains all the essential fatty acids and thus helps in case of Acne.
Skin healing:
Noni contain lipoic acid, betacarotene, protein, and vitamins A, C, and E. These ingredients reportedly repair damaged tissue and mitigate free-radical damage and thus helps in the healing process in acne
Cleansers: Noni acts like a good cleanser. Noni detoxify our body.
Antibacterial/anti fungal:
Noni for acne can help reduce inflammation, and infection. Acubin, L-asperuloside, and alizarin in the Noni have antibacterial activity as well as some other ingredients anthraquinone compounds are also proven antibacterial agents
Astringents: Noni acts like an effective astringents and remove excess facial oil.

The Role of Diet in Acne
Diet has long been suspected as a contributor to acne. Many people strongly believe that such foods as greasy pizza, chocolate and refined sugars cause acne. Meanwhile, the conventional dermatological community is adamant that diet does not contribute to acne, dismissing most dietary concerns as myths.

According to the few well-designed scientific studies, the truth is probably somewhere between these two extremes. There is some very preliminary evidence that a diet with a high glycemic index—that is, one contributing to glucose in the blood—may contribute to acne. Noni contain the carbohydrates of very low glycemic index value

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