Thursday, April 29, 2010

Distributors Required

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Wednesday, April 28, 2010



Asthma is primarily a disorder of the bronchial tubes, the airways that connect the windpipe (trachea) and the lungs. The bronchial tubes are surrounded by smooth muscle. The tubes themselves are lined with mucus glands and contain inflammatory immune-system cells called mast cells, lymphocytes, and eosinophils. When activated, these cells produce inflammatory mediators such as histamine and leukotrienes, which bind with receptors on cells within the bronchial tubes.

During as asthma attack, a cascade of events is launched that results in the production of histamine and leukotrienes. Leukotrienes are derived from the inflammatory arachidonic acid. These inflammatory mediators cause a host of changes in bronchial tissue: they trigger a dramatic increase in mucus secretion and a simultaneous rapid constriction of the bronchial smooth muscle, which narrows the bronchial tubes and reduces the amount of air that can pass through them. Over the course of the subsequent few hours, inflammatory cells move into the area, capillaries begin to leak fluid, and direct tissue damage occurs, triggering further inflammation and swelling. The net result is wheezing and coughing and eventual trapping of air in the alveoli (a tiny, thin-walled, capillary-rich sac in the lungs, or air sac) and smaller airways. This air trapping is most dangerous to the asthmatic because it progressively limits the amount of air that can be exchanged between the lungs and the blood stream, eventually causing rising carbon dioxide levels and falling oxygen levels. The increased muscular effort required to move air increases oxygen demand, tissue metabolism, and acid production, eventually resulting in exhaustion and, in extreme cases, respiratory collapse and arrest.


Higher levels of the antioxidants beta-carotene and vitamin C, along with the antioxidant trace minerals, were associated with a lower risk of asthma. The idea behind nutritional supplementation is to disrupt this inflammatory cascade whenever possible.

For example, omega-3 fatty acids have been shown to inhibit the production of arachidonic acid, which reduces the concentration of inflammatory leukotrienes . Other phytonutrients and flavonoids glycosides interfere with other causative factors in the inflammatory cascade, such as inhibiting nuclear factor kappa beta and an enzyme that converts arachidonic acid to leukotriene B4.

Scientists are also beginning to better understand the interaction between allergies, asthma, and oxidative stress. Oxidative stress occurs when highly reactive molecules, known as free radicals, interact with molecules within the body, especially DNA and mitochondrial membranes.

Experimental evidence suggests that some pollutants, such as vehicle exhaust, may produce oxidative stress in the bronchial tubes. Studies suggest that natural dietary supplementation with all nutrients and phyto nutrients like cysteine and alpha-lipoic acid, bio flavonoids , glycosides etc can enhance the pulmonary defenses, thus countering oxidative stress.
Antioxidants (vitamins C, E, and A). A number of studies have suggested that consuming antioxidants such as vitamins C, E, beta-carotene, flavonoids, selenium, and other nutrients reduces the risk of bronchoconstriction associated with asthma.
For instance, studies have shown that vitamin C and possibly vitamin E supplementation can alleviate the severity of asthma symptoms. Dietary supplementation with vitamin C and vitamin A has also been associated with reduced susceptibility to asthma attacks. Other studies have demonstrated that vitamin C or E supplementation may be a valuable addition to the treatment of patients with allergic rhinitis (otherwise known as hay fever) and asthma.

Dietary supplementation of vitamin C has also been found to help a specific form of asthma called exercise-induced asthma (EIA). People with EIA are usually symptom free when not exercising. Studies have found that 1 or 2 g vitamin C daily diminished episodes of EIA.
Flavonoids. Flavonoids have antioxidant properties and have been associated with improved lung function. One study demonstrated that a high dietary intake of the flavonoids was associated with a lower prevalence of asthma.

Noni acts as an effective and powerful anti-oxidant. It contains all the vitamins and minerals – Vita A, C, E, B1, B2, B6, B12, beta-carotene, Niacin, Biotin, Pantothenic Acid (B5), Folic Acid. Noni is rich with bio flavonoids, flavone glycosides, linoleic acid, Alizarin, amino acids, acubin, L-asperuloside, caproic acid, caprylic acid, ursolic acid, rutin, and proxeronine.
A research group has successfully identified several new flavonol glycosides, an iridoid glycoside from the Noni leaves, a trisacharide fatty acid ester, rutin, and an asperulosidic acid from the fruit. Besides that Noni contains more than 150 other essential phytonutrients that are highly required for our body

Therefore Noni may help to reduce the risk of bronco constriction associated with asthma. Anti oxidant property of Noni helps to reduce the oxidative stress and neutralizes the damaging effect of free radicals.

Hence a long term use of Noni helps for the asthmatic patients a lot.

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Noni Can help you in Arthritis

What is Arthritis?

Arthritis is an inflammation of one or more joints in the body, though the term is used to describe almost all problems associated with the joints. You may have heard of arthritis referred to as rheumatism. Rheumatic disease refers to any type of arthritis, rheumatism or musculoskeletal disease. There are over 100 conditions altogether, some rare and some common. Arthritis can affect anyone of any age, including children; however, arthritis tends to affect women more than men.

What types of arthritis and rheumatism are there?
There are many forms of arthritis and rheumatism. The most common forms of rheumatic disease are:
• Osteoarthritis - This is the most common form of arthritis. It is also known as degenerative joint disease. Osteoarthritis is more common after the age of 45 and is also more common in women. Osteoarthritis commonly affects weight bearing joints such as the knees, hips, spine and feet. However, you may also get osteoarthritis on smaller joints like the fingers, called Heberden' s nodes (painful, bony growths usually at the end of the fingers) that can make the hands appear knobby and sometimes out of shape. Osteoarthritis of the hands is more common in women as they go through the menopause.
• Rheumatoid arthritis (RA) - This is a type of inflammatory arthritis and is a common disorder, which causes inflammation, pain and stiffness in the joints. RA typically affects the small joints, such as the hands, wrists, elbows and feet. However, RA can affect any joint and can be the most disabling type of arthritis. RA is usually symmetrical - if a joint is affected on one side of the body the other side is also affected. Occasionally, RA can cause inflammation in other body organs such as the heart and lungs. It is known that RA is an autoimmune disease, which means the body's immune system reacts to something abnormal in the body and tries to remove it. In RA the immune system attacks the layers of healthy tissue that line the joint (known as the synovium). The synovium produces a thick lubricating fluid called synovial fluid. This fluid acts like an oil, which lubricates the joint allowing free movement. In RA the synovium becomes much thicker and may produce larger amounts of fluid, causing the joint to become painful, stiff and inflamed. If left untreated the joint can become permanently damaged, resulting in deformity.

• Gout - Gout is a painful type of arthritis that can attack both large and small joints, though it usually only attacks one joint at a time. The condition usually begins with pain in the big toe. Other joints that are affected include the wrists, fingers, ankles, knees and elbows. Gout is caused by high levels of a substance in the bloodstream called uric acid, this condition is known as hyperuricaemia. Uric acid normally forms when the body breaks down a natural chemical in foods called purines. Uric acid is also formed by the breakdown of the body's own tissues, such as blood cells. Uric acid is usually removed from the body by the kidneys and taken out of the body in urine. Uric acid levels can become raised if the kidneys, though healthy cannot get rid of uric acid fast enough or the body begins producing too much uric acid, due to an inherited tendency. Uric acid levels will also tend to be higher if you have kidney disease. When uric acid builds up in the bloodstream it overflows and forms sharp crystals that collect in the joints and soft tissues. The majority of people who have hyperuricaemia (high uric acid levels) will not develop gout.

• Fibromyalgia - Fibromyalgia is a chronic pain disorder that causes fatigue and widespread pain in the muscles, ligaments and tendons (the fibrous tissues in the body), but not the joints. The pain can affect all areas of the body, however, the tender points are usually in specific areas, such as the back of the head and neck, spine, hips, elbows and shoulders. Scientists are unsure of the cause of fibromyalgia. However, research indicates that people who suffer sleep disturbances regularly can develop fibromyalgia, for example if you suffer with arthritis and the pain disturbs your sleep you may go on to develop fibromyalgia (this is called secondary fibromyalgia). Fibromyalgia may also be triggered off during periods of stress or after a major trauma, such as a car crash or an operation, though usually the condition will develop without any obvious trigger.
• Systemic lupus erythematosus (SLE) or lupus for short is a connective tissue disease, which means it affects tissues throughout the body. Lupus commonly affects the skin, joints, heart, kidneys, lungs and occasionally the brain.

There is another form of lupus called Discoid Lupus Erythematosus (D.L.E.), which usually only affects the skin. This type is less serious and causes itchy red patches or lesions on the skin. These rashes usually occur on the face and neck but can appear on the palms of hands, soles of feet, scalp, elbows and fingertips. Lupus is an autoimmune disease, which means there is a fault in the body's immune system. Normally, the body produces certain chemicals called antibodies, which help the body fight infections, such as viruses. However, if you have an autoimmune disease, your body's immune system attacks its own cells and tissues. In lupus these antibodies, known as auto-antibodies are produced in large amounts causing the inflammation of tissues throughout the body.

• Juvenile arthritis - Juvenile arthritis refers to all types of arthritis that affect children. However, it is fortunately quite rare.

• Polyarthritis - This type affects five or more joints and is more common in girls. This type commonly affects smaller joints like the hands and feet, though larger joints may also be affected. It often affects the same joint on both sides of the body.

• Back pain - this is a common problem and can have a number of causes. Back pain is very common and a major cause of disability and people having days off work. The majority of back pain problems is not serious and only last a few days or weeks and will usually sort themselves out. Back pain might also be referred to as lumbago. Pain in the back usually comes from the muscles, ligaments and joints not moving as they should.

What are the symptoms of arthritis and rheumatism?
The symptoms you experience will depend greatly on the type of arthritis or rheumatism you are suffering with. However, the following symptoms may indicate that you have arthritis or rheumatism:
• Swelling in one or more joints.
• Stiffness around the joints.
• Joints that look red and can be warm to the touch.
• Constant or recurring pain in a joint that has no obvious cause.
• Sudden difficulty in moving or using a joint.

Any joint in the body can be affected by arthritis and rheumatism. However, the knees, fingers and hips are the joints most commonly affected.If you have rheumatoid arthritis you may also experience a mild fever and loss of appetite or energy. Symptoms of arthritis tend to be worse in the morning and sometimes in cold, damp weather. When the affected joints are moved you may hear a click or crack.

Cyclooxygenase (COX) enzyme and Arthritis, Pain, redness, heat, and swelling, which are the markers of inflammation, follow the release of prostaglandins. Aspirin and similar non-steroidal anti-inflammatory drugs (NSAIDS) reduce prostaglandins by blocking an enzyme which helps to produce them, called cyclooxygenase (COX).

In recent years some exciting studies have been published that shed light on how to more safely combat arthritis. There are actually two COX enzymes in the body. They are COX-1 and COX-2. COX-1 is called the good COX enzyme, while COX-2 has earned the unflattering name as the bad enzyme. COX1 is easily identifiable and is important in regulating cell function. COX2, on the other hand, is generally undetectable in most tissues, but increases to high levels during acute inflammation. The COX2 enzyme is largely responsible for causing pain and inflammation. Injury, disease, and trauma cause COX2 enzyme to produce prostaglandins, which cause pain and inflammation. In contrast to the COX-2 enzyme, COX-1 enzyme is responsible for protecting the body’s stomach lining and kidneys. COX-1 enzymes continually produce protective prostaglandins.

COX-1 is essential for blood clotting and for protecting the stomach. COX-2 is the key player in inflammation, pain, and fever. NSAIDs and other arthritis medication steeply decrease the body’s production of both enzymes, thereby decreasing inflammation while at the same time causing harm to the stomach and its lining. The ideal situation would be to find a substance that inhibited only COX-2, but did not significantly affect COX-1.

Noni and pain , Noni is a selective COX-2 inhibitor There are several other ways in which Noni may alleviate the undesirable symptoms of arthritis. Pain is the number one complaint with arthritis.

Researchers at an independent research facility found that indeed Noni was a selective inhibitor of COX-2 enzyme. In addition, the Noni did no damage to the COX1 enzyme. When scientists compared the Noni COX2 inhibition ratio of prescription arthritis medications, they found that Noni compared “very favorably” to the prescription medications. Yet, Noni exhibited none of the negative side effects that the prescription medications are known to cause. Next, researchers compared the Noni COX2 inhibition ratio to the COX2 inhibition ratio of NSAIDs. In this category, Noni far out-performed the over-the-counter medications. And again, the Noni did not exhibit any of the negative side effects associated with NSAIDs.

Role of Scopoletin present in Noni in arthritis and inflammation
Another reason for Noni’s pain fighting qualities may stem from several of its constituents. Noni has been shown to contain Scopoletin, which has anti inflammatory effects. Scopoletin is needed in the body for smooth joint movement. It also produces anti-histamine effects. A laboratory in France conducted a study that showed mice, given a liquid form of Noni, increased pain tolerance as reflected by their reaction time to a hot plate. The researchers concluded that Noni helped the mice better deal with the pain from the hot plate.

Noni in fibromyalgia
Fibromyalgia and chronic fatigue and immune dysfunction syndrome (CFIDS) is more than just psychological problems. Researchers have discovered that patients with fibromylgia have abnormalities in the brain and central nervous system. For example, Fibromyalgia patient have significantly less blood flow to the parts of the brain that deal with pain, and they have twice the level of the brain chemical called Substance P, which helps nervous system cells communicate with each other about painful stimuli.

Noni allows the body to produce more Nitric oxide, which has clinically been shown to improve blood flow. From one study, of the 2,399 Noni users that suffered from Fibromyalgia and CFIDS, 78% of them reported lessened symptoms after taking Noni juice
The primary cause of Fibromyalgia is the oxidative stress in our body by which our body is loaded with free radicals and that are not the only cause of fibromyalgia but the origin of uncountable health elements. A good nutritional supplement with rich in all antioxidants can save you from this disease. Only Noni contains lots and lots of most useful and all necessary micro nutrients and its powerful anti oxidant properties help in root out the disease and its unique property of pain reducing and other pharmacological property help a lot to manage the disease in acute cases.

The way in which Noni may help those suffering from this debilitating disease is by its perfect immune modulating and high antioxidant properties, however there are several theories. For instance, an increase in energy after taking Noni juice was reported by 90 percent of the 12,199 people in a survey who were drinking Noni juice. Since many Fibromyalgia and CFIDS folks suffer from loss of energy, an increase in energy from Noni is a very positive effect from the juice.

Noni and Rheumatoid Arthritis
Autoimmune diseases are the most complicated and obstinate type of disorders which doesn’t have any successful treatment plan in the present standard treatment line. The Rheumatoid arthritis is one among them. In this disease the body immunity system begins in attacking the cartilages and the synovial linings of joints, as a result an unbalanced inflammatory process begins significant destruction of healthy tissue. Studies also indicate that free radical production is 5 times higher in RA. A good proper nutritional supplement which will be effective in removal of free radicals from the body. Noni is the best nutritional supplement provider and also a powerful immune modulator of our body. In all auto immune disease especially in rheumatoid arthritis it needs to activate the body immune system to work in an optimal level so that we can prevent and can treat that disease. Rheumatoid arthritis and SLE are such type of diseases those are linked with the body immune system. In those diseases Noni may help a lot by modifying the body immune system. The inflammatory process found in that disease can successfully handle by the use of Noni. All the essential fatty acids present in Noni helps in this aspects

The micronutrients present in Noni. The Noni contain xeronine, all the vitamins, all necessary minerals and 17 amino acids out of 20 and 150+ nutraceuticals those helps in providing the body’s required micronutrients for a smooth and harmonious function of all our system in both health and diseases

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Anxiety disorders are illnesses that cause people to experience exaggerated fright and apprehension in response to external or internal stimuli. These conditions are often related to the biological and psychological makeup of the individual and may be familial in nature. If untreated, these illnesses can significantly reduce productivity and impair a person’s ability to function in daily life. Anxiety can occur independently or in conjunction with other psychiatric or medical conditions, such as depression, phobias, chronic fatigue, cardiac disease, or respiratory compromise. Moreover, chronic anxiety is associated with a higher risk of morbidity and mortality from cerebrovascular and cardiovascular diseases, such as hypertension, cardiac ischemia, and arrhythmias, and it predisposes people to a range of other disorders. Typically, anxiety disorders are treated with an array of psychoactive medications that alter or increase levels of neurotransmitters. Unfortunately, these medications also carry sometimes significant side effects, including the risk of dependency. A number of nutrients have been identified that act along pathways similar to those of prescription medications or have a general antianxiety effect.
Role of Noni
Anxiety, Homocysteine, and B Vitamins:
Various studies have conclusively linked decreased folate and elevated homocysteine to depressive disorders. However, little is known about the connection between elevated homocysteine and anxiety disorders. In recent years, a number of research teams around the world have conducted preliminary studies examining the possible role of elevated homocysteine in anxiety. The results have been intriguing.
In one study, for instance, 23 patients with Obsessive-compulsive disorder (OCD) were evaluated for folate and homocysteine levels, and their levels were compared with those of healthy control participants. Researchers found that folate levels were significantly lower in OCD patients than in controls and homocysteine levels were higher. Furthermore, the more severe the OCD, the more severe the folate deficiency. In light of this research, it may be prudent for people with anxiety disorders to also measure and supplement with folic acid and B vitamins to lower homocysteine, especially if they are also depressed. Noni contain rich quantity of folate and Vitamin B in a natural form. Hence supplementation of Noni in case of anxiety or OCD is better mode of treatment.

Amino acids. Amino acids, particularly neurotransmitter precursors, are essential to normal brain function. The ability of L-tryptophan and L-tyrosine to produce serotonin and norepinephrine varies directly with plasma concentrations of L-tryptophan and L-tyrosine and inversely with plasma concentrations of other large neutral amino acids. Depletion of serotonin and its precursor L-tryptophan increases symptoms of anxiety, particularly panic disorder. Noni helps naturally to elevate the secretion of serotonin in the brain. NONI juice contains 17 amino acids including all essential amino acids with those L-tryptophan and L-tyrosine too. Hence Noni will help a lot in case of the anxiety neurosis as it enhances the serotonin level in body.

Melatonin. Melatonin, a hormone made from serotonin, has neuroprotective and antioxidant properties, detoxifies free radicals, and stimulates antioxidative enzymes. Some research has shown that people with panic disorders have abnormal melatonin patterns. Noni helps to secret more melatonin from the pineal gland of our body.

Thus Noni may help in case of anxiety neurosis by stimulating more serotonin level in the blood.

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Tuesday, April 27, 2010

Noni the best Anti Agent

As the age increasing, one notices the skin losing its glow and becoming dry and rough. This is due to decrease in the moisture content of the stratum corneum or to a decrease in the moisture content of the stratum corneum or to a decrease in vertical height of epidermal cells.
Decrease in the number of Langerhans cells decreases the skins immune response. The reduction of Melanin and decreased immunity, increases the risk for tumorigenesis.

In elderly persons the dermis has a decreased density with fewer cells and blood vessels. The total amount of collagen decreases one percent per year in adulthood. Therefore the skin thickness decreases linearly with age after 20. the remaining collagen fibres become thicker, less soluble and more resistant to digestion by collagenase with age. Noni presents this.

The rate of nail growth also decreases with aging. Nail plates usually become thinner, more brittle and fragile. Hair graying occurs due to loss of functional melanocytes. Of course heredity also plays an important role in hair graying. A decrease in the number of hair follicles in the scalp increases baldness.

Collagen is one of the compounds of connective tissue which occurs not only within the dermis layer of the skin but also found in every organ and structure of human body. Connective tissue is composed of collagen fibres, elastic and the extracellular matrix but the amount and conformation of collagen is different in any given tissue.
Although flexible, collagen fibres offer a great resistance to any pulling force. Collagen fibres are fairly simple proteins and are made up of chains of amino acids. Amino acids are delivered from circulation to the cell called fibrocytes that manufacture collagen. The three important nutrients of collagen namely glycine, hydroxyproline, hydroxylysine are naturally present in Noni. Very rarely any other animal protein contains all the three of these nutrients.

With aging this collagen simply becomes metabolically inert. It loses its responsiveness, flexibility, fluidity, and strength. In the skin, the change in the quality of our collagen manifest as a loss of smoothness, plumpness, and luster. These changes are modifiable and largely preventable. Noni when used both internally and externally promotes the maintenance of healthy skin. The skin apart from protection also helps to absorb nutrients.

Noni because of its amphoteric nature that is the presence of fatty acid like linoleic acid as well as water, when applied externally aids healing of rashes, inflammation prickly heat, rosacens, or other allergic manifestations. These symptoms and allergy may be due to the release of histamine. Noni resists the release of histamine and protects the skin against allergies.

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An aneurysm is an abnormal widening or ballooning of a portion of an artery, related to weakness in the wall of the blood vessel. Some common locations for aneurysms include:

• Aorta (the major artery from the heart) -- see abdominal aortic aneurysm and thoracic aortic aneurysm)

• Brain (cerebral aneurysm)

• Leg (popliteal artery aneurysm)

• Intestine (mesenteric artery aneurysm)

• Splenic artery aneurysm

Causes, incidence, and risk factors
It is not clear exactly what causes aneurysms. Defects in some of the parts of the artery wall may be responsible. In certain cases (abdominal aortic aneurysms), high blood pressure is thought to be a contributing factor. Some aneurysms are congenital (present at birth).
Atherosclerotic disease (cholesterol buildup in arteries) may contribute to the formation of certain types of aneurysms. Pregnancy is often associated with the formation and rupture of aneurysms of the splenic artery (an artery leading to the spleen).

The symptoms vary depending on the location of the aneurysm. Swelling with a throbbing mass at the site of an aneurysm is often seen if it occurs near the body surface. Aneurysms within the body or brain often have no symptoms
In the case of rupture, low blood pressure, high heart rate, and lightheadedness may occur. The risk of death after a rupture is high.

Role of Noni
1. High blood pressure is thought to be a contributing factor of aneurysm.
NONI keeps high blood pressure in check:
The Role of Nitric oxide –
As we are well aware, hypertension has multifactor etiology. It is clear that diet, exercise, and genetics play a role in the human body’s circulatory function.
The level of nitric oxide is believed to be one controller of blood pressure within the body. Noni stimulates and boosts the body’s immune system, therefore enabling the body to produce more nitric oxide in the body. Recent studies have shown how specific extracts from Morinda citrifolia (NONI) produce a significant nitric oxide effect in endothelial cells in vitro. Nitric oxide acts as a vaso dilator to reduce the high blood pressure in hypertensive patient.
The Role of Scopoletin present in Noni to reduce the Hypertension-
Another key component found in Noni that has been connected to lowering blood pressure is scopoletin. Scopoletin, which has been scientifically proven to dilate blood vessels and act as a vaso dilator also helps in lowering the blood pressure.
Role of Xeronine , the alkaloid of Noni in reducing High Blood Pressure and cardiovascular diseases
Xeronine is a small alkaloid that is required in picro gram(trillionth of gram) amounts and is essential to the correct functioning of body. Large amount are used in times of physical or mental stress. In over mental stress condition the blood pressure rises hence the role of xeronine helps in lowering the blood pressure by maintaining the normal function of all cells, enzymes, and keeping all the endocrine system to act in a harmonious way.
The xeronine system promotes a healthy cell structure within the circulatory system thus maintain the blood pressure within the normal range.

The role serotonin in cardiovascular diseases
Serotonin is a neurotransmitter, a specialized molecule that allows nerve cells to communicate and interact with each other. Without neurotransmitters we would be unable to think, perceive, move, or even live. Serotonin also does double duty in the cardiovascular and gastrointestinal systems. It helps regulate the expansion and contraction of blood vessels and the function of platelets, the blood cells that cause blood to coagulate and close a wound. It is synthesized in different parts of the brain and body, where it can be stored or released. The most important raw ingredient is an amino acid called tryptophan. Noni is a good source for tryptophan. When we take Noni the amino acid tryptophan enters ours blood stream and are carried to tissues that will use them to synthesize the body's own proteins and other essential molecules, including serotonin.

2. Defects in some of the parts of the artery wall may be responsible for the formation of aneurysm
If the defect artery tissues are the free radical cause then Noni will help a lot as Noni is an efcetive antioxidant. Noni contain all antioxidant vitamins, all trace minerals, and lots of phyto chemicals. All phytochemicals have powerful antioxidant property. So Noni will help a lot to netralise the free radical damaging efcet over the artery tissues. Besides that Noni also increases the synthesis of antioxidant enzymes in our body . Noni also raise the glutathione level which is a potent antioxidant. Thus Noni protect the artery wall tissue from the oxidative stress injury and prevents the formation of aneurysm.

If the origin of defect of tye artery wall is some other cause then also Noni may help as Noni is rich with nutrients and micronutrients and thus it helps to rejuvinate the cells and also the xeronine alakloid of Noni helps to repair the damage cells. Hence Noni support the artery tissues and prevents it from any damage.

3. Atherosclerotic disease may contribute to the formation of certain types of aneurysms.
Noni prevents the Atherosclerotic changes inside the vessels
The high rise of cholesterol in our blood is one of the causes of atherosclerotic changes inside the vessels. Cholesterol is of two types – HDL (high density lipoprotein) cholesterol and LDL (low density lipoprotein) cholesterol. Among them HDL cholesterol is good for our body. But LDL cholesterol is named as bad cholesterol. . But LDL cholesterol is not really bad in its native form because God did not make a mistake when he created it. Native LDL cholesterol is good. In fact it is essential for building good cell membrane, others cell parts, and many different hormones that our body needs. Problems begin when native LDL cholesterols are oxidized by the free radicals in our body and make them the harmful cholesterol. The high environmental pollutions, our stressful life style, a good nutrients depleted diet are the main causes of over production of free radicals in our body. Those free radicals play the main role to oxidize LDL cholesterol and make it harmful to our body. So to neutralize the notorious activity of those free radicals to convert the native LDL cholesterol to harmful LDL cholesterol it is required some powerful antioxidants. Those antioxidants not only neutralize the effect of free radicals on the vessels cells but also to other cells. NONI have the powerful antioxidant properties that help to neutralize the free radicals role of oxidation of the native LDL cholesterol to harmful LDL cholesterol and thus protects the arterial endothelial lining from injury and future developing atheromatous plaque. The main antioxidants are vitamins A, E and C, beta-carotene, glutathione, bioflavonoid, selenium, zinc, CoQ10 (ubiquinone), and various phyto-chemicals. NONI is rich with Vita A, Beta carotene, Vita E, C, glutathione, bioflavonoid, selenium, zinc, and many more essential phytochemicals. Melatonin, a hormone produced by the pineal gland, is also a potent antioxidant. NONI helps to stimulate more melatonin release from the pineal gland.
Thus Noni prevents the atherosclerotic changes inside the vessels.

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How Noni is helpful in Anemia

Anemia is a common blood disorder characterized by a decrease in the amount of red blood cells, or a decrease in the capacity of red blood cells to transport oxygen. This results in a lack of oxygen reaching the body’s cells and tissues. Referred to as the “hidden hunger” by the World Health Organization, anemia poses significant health risks worldwide. Women are about twice as likely to be anemic as men. This is especially true of premenopausal women; between 4 percent and 8 percent of premenopausal women have iron deficiency anemia.
Anemia is associated with poor health outcomes. Anemia is associated with the following

• Weakness and fatigue
• Irritability
• Shortness of breath
• Headaches
• Sore tongue and bleeding gums
• Pallor
• Nausea and loss of appetite
• Faintness and dizziness
• Confusion and dementia
• Increased heart rate
• Heart failure (in severe cases)

Depending on its cause, anemia is generally classified in three ways: excessive bleeding, decreased red blood cell production, or increased red blood cell destruction.

Excessive bleeding
This form of anemia occurs when someone loses too much blood, either because of an injury (acute anemia) or a chronic disease. When the body loses a large amount of blood, the body reacts by pulling water from surrounding tissues into blood vessels to maintain a healthy blood pressure. This dilutes the blood, lowering the proportion of red blood cells.
Excessive bleeding can result in very serious anemia, depending on the nature of the injury. However, anemia related to chronic conditions, such as recurrent nosebleeds or ulcers in the stomach, develops more slowly and may not be as obvious. This type of anemia sometimes occurs as a result of cancer, especially colon cancer.
Chronic blood loss can cause a deficiency in iron. Iron deficiency anemia is the most common form of anemia. It results in decreased red blood cell production.
Because it can take several months to deplete the body’s supply of iron, it might take a long time for symptoms to develop. In women, this condition is frequently related to excessively heavy menstrual bleeding; in men, it is often related to gastrointestinal bleeding.
Decreased red blood cell production

Red blood cells are manufactured in the bone marrow. This process relies on various nutrients, including iron, vitamin B12, and folic acid, as well as smaller amounts of vitamin C, riboflavin, and copper. Also, the production of red blood cells is stimulated by a hormone called erythropoietin. Deficiencies in any of these nutrients or in erythropoietin can result in anemia. Besides iron deficiency anemia caused by bleeding, other forms of anemia include:

• Pernicious anemia (vitamin B12 deficiency)— Vitamin B12 deficiency is rarely related to a dietary deficiency. Rather, vitamin B12 relies on intrinsic factor, a protein generated by cells in the stomach, to be bound to vitamin B12 and then absorbed in the ileum, the last segment of the small intestine. People who lack intrinsic factor cannot use the available vitamin B12, meaning that anemia can develop even if large amounts of vitamin B12 are consumed. Besides a lack of intrinsic factor, pernicious anemia can be caused by Crohn's disease, stomach surgery, or a strict vegetarian diet.

• Folic acid deficiency anemia—folic acid deficiency is more common than pernicious anemia. Folate deficiency is found in malnourished individuals (especially alcoholics), infants who are fed only cows’ milk, pregnant women, and adults over age 60. It can also be caused by diseases that affect absorption in the small intestine, including Crohn's disease.

• Anemia of chronic disease—Anemia is associated with various chronic diseases and conditions, including infections, inflammatory diseases, and cancers, HIV/AIDS.

• Additionally, aplastic anemia is a rare form of anemia that occurs when bone marrow fails to produce all three types of blood cells: red blood cells, white blood cells, and platelets. Causes of aplastic anemia include autoimmune diseases, viruses, or chemicals. Symptoms include frequent infections (white blood cells are reduced), fatigue (red blood cells are reduced), and bleeding (platelets are reduced).

Increased red blood cell destruction
If the rate of red blood destruction is more rapid than the creation of new red blood cells, hemolytic anemia occurs. Hemolytic anemia can result from infection, certain drugs, autoimmune disorders in which the body attacks and destroys its own red blood cells, and inherited disorders such as sickle cell anemia or thalassemia.

Additionally, an enlarged spleen can result in anemia. The spleen is responsible for destroying old red blood cells; an enlarged spleen can increase the rate of red blood cell destruction beyond the body’s ability to manufacture new red blood cells.

Role of Noni

• In iron deficiency anemia Noni may help to provide the iron, folic acid in natural form.

• Symptoms of folic acid deficiency may include diarrhea and other gastrointestinal problems. Because supplementation with folic acid can mask a vitamin B12 deficiency, folic acid and vitamin B12 should be taken together. Noni contain folate and Vitamin B 12 including all the vitamins. Thus help in case of anemia. In pernicious anemia, the body lacks intrinsic factor, which is needed to carry vitamin B12 from the digestive tract into the bloodstream. This condition often affects the gastrointestinal tract and the nervous system, with symptoms that range from weakness to vertigo to angina. Noni may enhance the intrinsic factor in blood and thus help in pernicious anemia

• Trace minerals can be an adjunctive nutritional therapy to reduce the effect of anemia on normal red blood cell function. Copper, zinc, and selenium are used in biochemical processes such as cellular utilization of oxygen, DNA and RNA reproduction, maintenance of cell membrane integrity, and sequestration of free radicals. Noni contain all essential trace minerals and thus helps in anemia

• It has been found that a regular use of Noni enhances the Hb% in blood. As Noni contain all the macro and micro nutrients thus help a lot in case of anemia

• Noni also helps therapeutically the condition of cancer and AIDS which are one of the cause of anemia.

• There are many autoimmune diseases that develop anemia. Noni is a powerful immunomodulator and thus help in various autoimmune diseases and helps in case of anemia too

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